Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP1 All Species: 27.28
Human Site: T5 Identified Species: 40.02
UniProt: P36776 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36776 NP_004784.2 959 106489 T5 _ _ _ M A A S T G Y V R L W G
Chimpanzee Pan troglodytes XP_001143873 959 106437 T5 _ _ _ M A A S T G Y V R L W G
Rhesus Macaque Macaca mulatta XP_001088663 909 101136 T5 _ _ _ M A A S T G Y V R L W G
Dog Lupus familis XP_854391 960 106631 T5 _ _ _ M A A G T G Y V R L W G
Cat Felis silvestris
Mouse Mus musculus Q8CGK3 949 105824 T5 _ _ _ M A A S T G Y V R L W A
Rat Rattus norvegicus Q924S5 950 105774 T5 _ _ _ M A A S T G Y V R L W A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506549 791 89382
Chicken Gallus gallus XP_001232112 790 89040
Frog Xenopus laevis Q2TAF8 856 94553 G5 _ _ _ M A S S G S I Q I P R R
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 S5 _ _ _ M S S N S G I Q I P S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649133 1006 112875 A5 _ _ _ M L A R A I R V R P M M
Honey Bee Apis mellifera XP_392970 995 112847 F9 R F M T A V N F K I L S I F R
Nematode Worm Caenorhab. elegans O44952 971 108188 G5 _ _ _ M Y R A G A V L L R G A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P93648 964 105641 V6 _ _ M L R A A V A A A E E L R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93655 940 103912 S7 _ M L K L F T S S A S R V H H
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 T17 L S T V A R T T R A I Q Y Y R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 86.6 93.7 N.A. 87.4 88.6 N.A. 71.6 73.8 32.2 32.7 N.A. 59.4 58.9 51.5 N.A.
Protein Similarity: 100 99.6 89 96 N.A. 92 92.8 N.A. 77 78.5 50.8 52.3 N.A. 73.3 74.9 67.2 N.A.
P-Site Identity: 100 100 100 91.6 N.A. 91.6 91.6 N.A. 0 0 25 16.6 N.A. 33.3 6.6 8.3 N.A.
P-Site Similarity: 100 100 100 91.6 N.A. 91.6 91.6 N.A. 0 0 33.3 50 N.A. 33.3 33.3 25 N.A.
Percent
Protein Identity: N.A. 48.7 N.A. 48.1 39.1 N.A.
Protein Similarity: N.A. 65.8 N.A. 65.4 57.1 N.A.
P-Site Identity: N.A. 7.6 N.A. 7.1 13.3 N.A.
P-Site Similarity: N.A. 23 N.A. 28.5 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 57 50 13 7 13 19 7 0 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % E
% Phe: 0 7 0 0 0 7 0 7 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 0 0 0 7 13 44 0 0 0 0 7 25 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % H
% Ile: 0 0 0 0 0 0 0 0 7 19 7 13 7 0 0 % I
% Lys: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % K
% Leu: 7 0 7 7 13 0 0 0 0 0 13 7 38 7 0 % L
% Met: 0 7 13 63 0 0 0 0 0 0 0 0 0 7 7 % M
% Asn: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 13 7 0 0 0 % Q
% Arg: 7 0 0 0 7 13 7 0 7 7 0 50 7 7 32 % R
% Ser: 0 7 0 0 7 13 38 13 13 0 7 7 0 7 0 % S
% Thr: 0 0 7 7 0 0 13 44 0 0 0 0 0 0 0 % T
% Val: 0 0 0 7 0 7 0 7 0 7 44 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 38 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 38 0 0 7 7 0 % Y
% Spaces: 75 69 63 0 0 0 0 0 0 0 0 0 0 0 0 % _